It is neither the point in space, nor the instant in time, at which something happens that has physical reality, but only the event itself. ... The circumstance that there is no objective rational division of the four-dimensional continuum into a three-dimensional space and a one- dimensional time continuum indicates that the laws of nature will assume a form which is logically most satisfactory when expressed as laws in the four-dimensional space-time continuum.
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Published before 1923